檢查卵巢功能新工具microRNAs

2014.08.09

 目前我們都用AMH來檢查卵巢功能，但最新的研究剛出爐，在不孕症的權威期刊－《生育與節育期刊》2014年6月份，有人做出卵巢裡面的微RNA（microRNAs），也許將來能夠作為更精準的工具。

 
Regulatory role of microRNAs in ovarian function.Fertil Steril. 2014 Jun;101(6):1524-1530. doi: 10.1016/j.fertnstert.2014.04.024.
Regulatory role of microRNAs in ovarian function.
Imbar T1, Eisenberg I2.
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Abstract
MicroRNAs have recently begun to be explored in ovarian cells, uncovering their influence on fundamental ovarian features like steroidogenesis, ovulation, and curpos luteum development and function. We provide a review of the current knowledge on microRNAs, specifically relating to human ovarian cell function and microRNAs' role in the ovarian physiologic process and ovulation dysfunction. Because of microRNAs' known stability in body fluids, we enlighten also their potential use in the clinical setting as novel biomarkers for ovarian function. Future research of the role of microRNAs in physiologic and dysfunctional ovulation may offer new diagnostic and treatment strategies for infertility and other ovarian disorders.
Copyright © 2014 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.