挑選出好的精子試管嬰兒就成功一半了PF－1 SPERM RIGHT 我們知道好的卵子，如果遇到染色體異常的精子，不是不能懷孕，就是懷孕流產， 這樣比喻好了，有點是像一個美女嫁錯丈夫，我們知道嫁錯郎君是悲劇的開始， 又好像是一朵鮮花插在牛糞上， 因此如何選出染色體正常的精子？ 這裡介紹兩種方法， （1）一種是界面閥型微流體晶片，這個研究報告在2014年5月份，中國大陸有一份研究，發現到應非侵襲性，可以正確挑出正常染色體的精子，這個應該是最有淺力， （2）第二種方法是用螢光染色，以前我們是用TUNEL測驗，如果綠色代表精蟲DNA受損，並不是每一家試管嬰兒中心都能做這個TUNEL測驗，另外最近的發展是用: 螢光染色PF-1的螢光染色，可以找出精子染色體正常， 不管是第一晶片或是第二種的: 螢光染色PF-1，目的是一樣的，希望挑到夢幻奇精，染色體正常鏡子，也就是讓好不容易打針取到的卵子，能夠嫁給如意郎君，我們說有一個叫做MR　RIGHT應該我把它改寫為SPERM RIGHT 簡單一句話找對精子試管嬰兒就成功一半。 ============================================================ 1尋找夢幻精子的最新方法：使用界面閥型微流體晶片，找出最佳精子The construction of an interfacial valve-based microfluidic chip for thermotaxis evaluation of human sperm. 在2014年有一份3月份的研究他們使用最新的界面閥型微流體晶片，去找最好的精子，我們都知道好精子、好卵子就是好胚胎的保證，但是好的精子怎麼看？ 我們可以用IMSI， 我們也可以使用PICSI， 可是現在的報告好像IMSI PICSI沒有很好的結果， 這個最新的儀器界面閥型微流體晶片，請看照片，應該是地表上最新找精子的方法。 Zhonghua Nan Ke Xue. 2014 May;20(5):452-9. [Application of microfluidics in sperm isolation and in vitro fertilization]. [Article in Chinese] Li FF, Wang XY, Zhou SM, You F. Abstract Due to the low effectiveness of traditional assisted reproductive technology (ART), new technological possibilities are constantly explored. Lots of studies have demonstrated the potential of microfluidics to revolutionize the fundamental processes of in vitro fertilization (IVF). With the advantages of high efficiency, short time, harmless collection, real-time observation of separation, similar microenvironment, and automation, the application of microfluidics in sperm isolation andIVF has shown an evident superiority over the conventional approaches and provided a new platform for ART. This review highlights the application of various microfluidic techniques in sperm motility assessment and isolation, sperm chemotaxis assay, IVF, sperm concentration, and sperm separation and enrichment in recent years. It also briefly introduces the basic principles, structural design, and operation processes of the microfluidic platform, focusing on the advantages and disadvantages of each method and the potential of their clinical application. Obviously, there are still some challenges to the application of microfluidics in ART. However, it is believed that the development of this new technology would be toward a highly integrated application of several steps in one single device, known as IVF-lab-on-a-chip. PMID: 24908739 [PubMed - in process] Publication Types